Ion Personal Genome Machine™ (PGM™) System
The Ion Personal Genome Machine (PGM) System combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data, democratizing sequencing and making it accessible to your lab.
Device Type
Next Generation DNA Sequencer
Application Area
Molecular
Client
Thermo Fisher Scientific
Role of BIT
Manufacturing, After-Sales Services
History
2009 - 2012 (Transferred to inhouse manufacturing)
The Ion Personal Genome Machine (PGM) System combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data, democratizing sequencing and making it accessible to your lab.
This established system leverages the exponential improvements in the semiconductor industry (known as Moore’s Law) to provide scalability and flexibility for various applications.
The Ion PGM System uses natural sequencing chemistry, which eliminates the need for expensive optics and reduces complex chemistries to measure natural DNA extension. The system leverages direct, real-time sequencing detection, providing sequencing results typically in 3–7 hours.
| Test Type | Next Gen Sequencing |
| Sample Types | gDNA from Peripheral Whole Blood |
| Sample Volume | 5-10 ng |
| Assay Applications | Cancer Research, Inherited Disease Research, Microbial Genomics, Stem Cell Research, Agriculture, Epigenomics, Metagenomics, Forensic Science, Ancient DNA genomics |
| Throughput | Up to 2 Gb per run |
| Walk Away Time | 90 min |
| Time to First Result | 3-7 h |
| Analysis Type | Post-Light™ Ion Semiconductor Sequencing |
| Sample Loading Capabilities | Manual Processing |
| Input & Output | RS232 Ethernet 4 x USB |
| Interface | Touchscreen User Interface |
| Dimensions | 53 cm x 61 cm x 51 cm (H x W x D) |
| Weight | 30 kg |
| Power | AC 100 – 240 V 50/60 Hz 200-300 W |
